Cupressuflavone

Cupressuflavone

Common Name: Cupressuflavone

Synonyms: 8,8''-Bisbaicalein; Neorhusflavone; 8,8"-Biapigenin

CAS Registry Number: 3952-18-9

InChI:

InChIKey:

Formula: C30H18O10

Molecular Weight: 538.46

Exact Mass: 538.09

NMR Solvent: DMSO-d6 (1H), pyridine-d6 (13C)

MHz: 400 (1H), 100 (13C)

Calibration: not indicated

NMR references: Wollenweber, E., Kraut, L., Mues, R. (1998). External Accumulation of Biflavonoids on Gymnosperm Leaves. Z. Naturforsch. 53c, 946-950.

Shrestha, S., Park, J., Lee, D., Cho, J., Cho, S., Yang, H., Yong, H., Yoon, M., Han, D., Baek, N. (2012). Rhus parviflora and its biflavonoid constituent, rhusflavone, induce sleep through the positive allosteric modulation of GABAA-benzodiazepine receptors. J. Ethnopharmacol. 142, 213-220.

Species: See reference: Wollenweber, E., Kraut, L., Mues, R. (1998). External Accumulation of Biflavonoids on Gymnosperm Leaves. Z. Naturforsch. 53c, 946-950.

Notes: 13C NMR data obtained from Shrestha, S., Park, J., Lee, D., Cho, J., Cho, S., Yang, H., Yong, H., Yoon, M., Han, D., Baek, N. (2012). Rhus parviflora and its biflavonoid constituent, rhusflavone, induce sleep through the positive allosteric modulation of GABAA-benzodiazepine receptors. J. Ethnopharmacol. 142, 213-220.

Proton NMR Peaks

Position PPM Peak Type J (Hz)
3 6.76 s
6 6.4 s
2' 7.45 d 8.7
3' 6.72 d 8.8
5' 6.72 d 8.8
6' 7.45 d 8.7
3" 6.76 s
6" 6.4 s
2''', 6''' 7.45 d 8.7
3''', 5''' 6.72 d 8.8
5-OH 13.15 s
5"-OH 13.15 s

Carbon NMR Peaks

Position PPM
2, 2" 164.67
3, 3" 103.7
4, 4" 183.02
5, 5", 4', 4''' 162.56
6, 6" 99.86
7, 7" 162.76
8, 8" 100.16
9, 9" 156.45
10, 10" 105.34
1', 1''' 122.51
2', 6', 2''', 6''' 128.75
3', 5', 3''', 5''' 116.9